Already a member?
Sign in
Welcome! Wikis are websites that everyone can build together. It's easy!
Gonorrhea
Gonorrhoea is an STI commonly affecting the columnar and transitional epithelium of the urethra, endocervix, rectum, pharynx or conjunctiva, depending on the site of inoculation of the causative bacteria, Neisseria Gonorrhoea. N. Gonorrhoeae is a non-motile, non-spore-forming Gram negative diplococci. Humans are the only host to this organism.
Gonorrhoea is the commonest STI in PNG, with 5588 new cases reported annually (incidence 131/100 000). This figure is lower than the actual figure because of under-reporting. Cases peaked in the 1970s but reduced during the 1980s and early 1990s. These have been attributed to the safe sexual practices arising from HIV awareness. After an incubation period of 2-6 days, infected individuals usually present with urethritis, a syndrome characterised by purulent urethral discharge, dysuria and an increase in PMN leucocytes. Frequent urination, itchy meatus and abnormal menstruation (in females) are also common. Infections of extragenital sites are usually asymptomatic but can present with rectal bleeding/discharge/pain (anorectal gonorrhoea), vaginal discharge (cervicitis) or exudative tonsillitis (pharyngeal gonorrhoea). Infection of the mucosal surface by N. Gonorrhoeae involves attachment to the epithelium (mediated by the pilin and Opa, two surface bacterial proteins) and the evasion of the host defence mechanisms.
The epithelial integrity is disrupted, leading to the above symptoms.
Complications of the infection include ophthalmia neonatorum in infants (exposure during birth), gonococcemia (characterised by fever, polyarthralgia and pustular, hemorrhagic skin lesions), acute arthritis, and ascending infections (prostatitis and epididymitis in male; cervicitis and PID in females). Laboratory diagnosis of gonorrhoea is made by Gram stain of the urethral discharge (N Gonorrhoea is Gram negative diplococci) and culture in the Thayer- Martin medium. DNA amplification tests (PCR/LCR) are also available for accurate diagnosis.
Treatment is usually chemotherapeutic, using amoxicillin, Augmentin, probenecid and doxycycline. Education and screening sexual contacts are also vital components of management.
Gonorrhoea is the commonest STI in PNG, with 5588 new cases reported annually (incidence 131/100 000). This figure is lower than the actual figure because of under-reporting. Cases peaked in the 1970s but reduced during the 1980s and early 1990s. These have been attributed to the safe sexual practices arising from HIV awareness. After an incubation period of 2-6 days, infected individuals usually present with urethritis, a syndrome characterised by purulent urethral discharge, dysuria and an increase in PMN leucocytes. Frequent urination, itchy meatus and abnormal menstruation (in females) are also common. Infections of extragenital sites are usually asymptomatic but can present with rectal bleeding/discharge/pain (anorectal gonorrhoea), vaginal discharge (cervicitis) or exudative tonsillitis (pharyngeal gonorrhoea). Infection of the mucosal surface by N. Gonorrhoeae involves attachment to the epithelium (mediated by the pilin and Opa, two surface bacterial proteins) and the evasion of the host defence mechanisms.
The epithelial integrity is disrupted, leading to the above symptoms.
Complications of the infection include ophthalmia neonatorum in infants (exposure during birth), gonococcemia (characterised by fever, polyarthralgia and pustular, hemorrhagic skin lesions), acute arthritis, and ascending infections (prostatitis and epididymitis in male; cervicitis and PID in females). Laboratory diagnosis of gonorrhoea is made by Gram stain of the urethral discharge (N Gonorrhoea is Gram negative diplococci) and culture in the Thayer- Martin medium. DNA amplification tests (PCR/LCR) are also available for accurate diagnosis.
Treatment is usually chemotherapeutic, using amoxicillin, Augmentin, probenecid and doxycycline. Education and screening sexual contacts are also vital components of management.
Latest page update: made by dr.rufusrajadurai
, Nov 28 2007, 4:32 PM EST
(about this update
About This Update
Edited by dr.rufusrajadurai
view changes
- complete history)
Edited by dr.rufusrajadurai
view changes
- complete history)
Keyword tags:
gonorrhea
PCR
PID
sexually transmitted diseases
std
urethritis
More Info: links to this page
| Started By | Thread Subject | Replies | Last Post | |
|---|---|---|---|---|
| dr.rufusrajadurai | Good work Hogande | 0 | Nov 27 2007, 2:23 AM EST by dr.rufusrajadurai | |
|
|
Thread started: Nov 27 2007, 2:23 AM EST
Watch
Hi Hogande I saw the new page about gonorrhea that you have made here.
Itz really nice It is amazing.. keep going forward.. wishes, Dr.Rufus |
|||